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Chronic myeloid leukaemia (CML)

What is chronic myeloid leukaemia (CML)?

Chronic myeloid leukaemia (CML) is a type of cancer that affects the blood and . The leukaemia develops from early called myeloid blood stem cells. CML usually develops very slowly. 

There are different types of leukaemia. The treatment you need depends on the type you have.

Read about the other types of leukaemia

Last reviewed: 29 May 2025

Next review due: 29 May 2028

Risks and causes of CML

We don’t know what causes most cases of chronic myeloid leukaemia (CML). But we know that exposure to radiation can increase your risk of developing CML.

Survival for CML

Survival for chronic myeloid leukaemia (CML) depends on several factors including age. These figures can only give you a general guide about survival for CML.

Stages (phases) of CML

There are 2 systems to describe how far your CML has developed. You might have 2 or 3 phases. At the moment CML is mainly described using 3 phases. These are chronic, accelerated and blast. Knowing the phase helps your doctor decide which treatment you need.

Treatment for CML

Targeted cancer drugs called tyrosine kinase inhibitors (TKIs) are the main treatment for CML. Find out more about your treatment options, the different treatments and how they monitor treatment is working.

Living with CML

Chronic myeloid leukaemia (CML) is often a slowly developing condition. Treatment can keep it under control for many years. Find out how to cope and what support is available.

CML main page

CML starts in the white blood cells called granulocytes. It often develops slowly and treatment can keep it under control for many years. Find out more.

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