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Hormone therapy for prostate cancer

Surgery to remove your testicles (orchidectomy)

Surgery to remove your testicles is a type of hormone therapy for prostate cancer. But it is not a common treatment choice.

The testicles produce testosterone, which can help prostate cancer grow. So removing the testicles can help to control the growth of prostate cancer. After removing the testicles, the level of testosterone in the blood falls quickly. An operation to remove your testicles is called an orchidectomy.

Having an orchidectomy doesn't cure prostate cancer. But it can control the cancer and reduce your symptoms.

Some men prefer to have this surgery as it is one treatment compared to having regular injections. Orchidectomy is not reversible. You may find the removal of your testicles upsetting.

Find out more about hormone therapy for prostate cancer

Possible risks

Your doctors will make sure the benefits of having the surgery outweigh the possible risks. Risks of any operation include:

  • pain and discomfort

  • bleeding

  • infection

Risks of having surgery to remove both testicles include:

  • hot flushes

  • difficulty getting an erection 

This surgery may also affect your ability to have children. Talk to your doctor if having children is important. They usually suggest sperm banking before having surgery.

Possible changes to your sex drive and becoming infertile can be difficult to come to terms with. Talking to someone about this could help. This could be a close friend or a professional.

Find out more about sex and relationships and prostate cancer

Follow up

You will have a follow up appointment 6 weeks or so after your surgery. At the appointment your doctor:

  • examines you

  • asks you about how you are and if you have had any problems  

It is also your chance to ask any questions. Write down any questions you have before your appointment to help you remember what you want to ask. Taking someone with you can help you to remember what the doctor says.

After your first check up you will continue to have follow up to monitor your cancer. How often you have checkups varies. Ask your doctor how often you need to have checkups and what they will involve.

Last reviewed: 04 Jul 2025

Next review due: 04 Jul 2028

Surgery to remove prostate cancer

Surgery to remove your prostate gland is called radical prostatectomy. Most people in the UK have robotic assisted keyhole surgery.

What is hormone therapy?

Hormone therapy is a possible treatment for prostate cancer. You might have it with radiotherapy for prostate cancer that hasn't spread to distant body parts.

Treatment options for prostate cancer

Your specialist doctor discusses whether you need treatment, and what your treatment options are. Treatment options might include surgery or radiotherapy.

Living with effects of hormone therapy

Hormone therapy for prostate cancer can affect the levels of your hormones. This can cause different side effects including hot flushes, swollen breasts, sleep disturbances and weight changes.

Sex and relationships

Prostate cancer treatments can affect your sex life in different ways. Some treatments can damage the nerves or affect hormone levels that you need to get an erection.

Prostate cancer main page

Prostate cancer is cancer that starts in the prostate gland. The prostate gland is found at the base of the bladder and is about the size of a walnut.

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