Before making your application
- You must discuss the suitability of your proposal with the Centre for Drug Development
- Please email drugdev@cancer.org.uk
Overview of the application process
Applications follow a two-stage process:
- Confidential, informal discussions with the Centre for Drug Development to establish eligibility and suitability
- Formal application and review by the New Agents Committee
Confidential discussion
Email us to request a discussion. If required, we will set up a Confidential Disclosure Agreement to protect your data.
Please include a short project outline. For us to conduct an internal review to determine suitability under this scheme, we typically require the following information (if available):
- Project background and stage of development
- Agent manufacture information and physicochemical properties
- Target and scientific rationale, including mechanism of action
- In vitro and in vivo data including efficacy, toxicology and PK/PD
- Data or hypothesis-driven rationale for proof of mechanism biomarker and proof of principle/efficacy biomarker
- Summary of preclinical or clinical studies proposed
- The criteria that would constitute a successful study
- IP position
- Next steps in development
- Agent’s USP or competitive advantage over other similar agents in development
Key considerations we look for in projects at this stage include:
- Novelty
- Strength of scientific rationale
- Adequacy of preclinical data package
- Potential application in patients
We will provide feedback on your proposal and advise if it is ready for a formal application and review.
Formal applications
- You must submit a data package through our online Grants Management System.
- New Agents Committee: you will be invited to attend the meeting or join online to give a brief overview and address any questions from Committee members. The Committee will consider your application.
- You will receive the NAC's decision within 2 weeks.
All NAC proposals and panel meetings are confidential.
Kate Searle